Students : Student Publications

Student Publications

NAME: Brandon Kitay – PROGRAM: Neuroscience- YEAR OF STUDY: MS4 – MENTOR: Grace Zhai, Ph.D.

Kitay, KM, McCormack R, Wang Y, Tsoulfas P, and Zhai RG (2013) Mislocalization of neuronal mitochondria reveals regulation of Wallerian degeneration and NMNAT/WLDS-mediated axon protection independent of axonal mitochondria. Hum Mol Genet. Jan 11. [Epub ahead of print] PubMed PMID: 23314018; PubMed Central PMCID: PMC3657477. *Cover article

Petruska JC, Ichiyama R, Kitay BM, Boyce V, Kaspar B, Pearse D, Roy RR, Edgertone VR, Gage F, Mendell LM. 2010,Intramuscular AAV-NT3 alters synaptic transmission and motoneuron cellular properties in intact and spinal cord-injured rats. Eur J Neurosci. Sep;32(6):997-1005. doi: 10.1111/j.1460-9568.2010.07392.x. Epub 2010 Sep 8. PMID: 20849530

Ali YO, Kitay BM, and Zhai RG, 2010, Dealing with misfolded proteins: examining the neuroprotective role of molecular chaperones in neurodegeneration. Molecules 15(10):6859-87. PubMed PMID: 20938400; PubMed Central PMCID: PMID: 20938400

NAME: Taylor Schreiber- PROGRAM: Cancer Biology- YEAR OF STUDY: MS4 – MENTOR: Eckhard Podack, M.D.,Ph.D.

Schreiber TH, Bodero M, Wolf D, Gonzalez L, Podack ER. 2012, T Cell Costimulation by TNFRSF4 and TNFRSF25 in the Context of Vaccination. Journal of Immunology; 189(7):3311-8. PMID: 22956587

Schreiber TH, Wolf D, Bodero M, Podack ER. Tumor Antigen Specific iTreg Accumulate in the Tumor Microenvironment and Suppress Therapeutic Vaccination. OncoImmunology 2012;1(5):642-48. PMID: 22934256

Schreiber TH, Wolf D, Tsai MS, Chirinos J, Deyev VV, Gonzalez L, Levy RB, Podack ER. TNFRSF25 Mediated in vivo Expansion of Regulatory T Cells to Control Autoaggressive Disease. J Clinical Investigation 2010;120(10):3629-40. PMID: 20890040

Zhang Y, Eliav Y, Shin S, Schreiber TH, Podack ER, Tadmor T, Rosenblatt JD. 2013, B Lymphocyte Inhibition of Anti-Tumor Response Depends on Expansion of Treg but is Independent of B Cell IL-10 Secretion. Cancer Immunology Immunotherapy, 62(1);87-99. PMID: 22772949

Wolf D, Schreiber TH, Tryphonopoulos P, Li S, Tzakis AG, Ruiz P, Podack ER. 2012, Tregs Expanded In Vivo by TNFRSF25 Agonists Promote Cardiac Allograft Survival. Transplantation;94(6):569-74. PMID: 22902792

Khan SQ, Tsai MS, Schreiber TH, Wolf D, Deyev VV, Podack ER. 2013, Cloning, expression and functional characterization of mTL1A-Ig. Journal of Immunology 2013:190(4);1540-50. PMID: 23319737

Reddy P, Schreiber TH, Rajasagi NK, Mulik S, Niki T, Hirashima M, Podack ER, Rouse BT. 2012, TNFRSF25 Agonistic Antibody and Galectin-9 Combination Therapy Control Herpes Simplex Virus-Induced Immunoinflammatory Lesions. Journal of Virology 86(19):10606-20. PMID: 22811539

NAME: Randall Brenneman – Program: Cancer Biology – YEAR OF STUDY: Postdoc – MENTOR: Eli Gilboa, PhD

Berezhnoy, A., Brenneman, R., Bajgelman, M., Seales, D. & Gilboa, E. 2012,
Thermal stability Of siRNA modulates aptamer-conjugated siRNA inhibition.
Molecular Therapy: Neucleic Acids. PMCID:3499696

NAME: Brittany Ashlock- PROGRAM: Microbiology & Immunology – YEAR OF STUDY: MS4 – MENTORS: Enrique Mesri, Ph.D.

Daftarian P, Chowdhury R, Wei C, Ames P, King A, De Rivero Vaccari J, Dillon L, Price J, Moraes C, Leung H, Ashlock B, Mesri E, Züchner S, Reiser J, Lemmon V, Keane R., 2011, In vivo electroporation and non-protein based screening assays to identify antibodies against native protein conformations, Hybridoma, 22008067

Bhatt S*, Ashlock BM*, Toomey NL, Diaz L, Lossos IS, Mesri EA, Ramos JC, 2013, Efficacious proteasome/HDAC inhibitor combination therapy for primary effusion lymphoma, Journal of Clinical Investigation, PMID:23635777,*Co-first authors

Bhatt S, Ashlock BM, Natkunam Y, Sujoy V, Chapman JR, Ramos JC, Mesri EA, Lossos IS, 2013, CD30 Targeting with Brentuximab Vedotin- a Novel Therapeutic Approach to Primary Effusion Lymphoma, Blood, 2013 July 7: PMID 23838350

NAME: Howard Leung- PROGRAM: Cancer Biology – YEAR OF STUDY: MS4 – MENTOR: Enrique Mesri, PhD

Leung HJ, Duran EM, Kurtoglu M, Andreansky S, Lampidis TJ, Mesri EA. Antimicrob Agents Chemotherapy, 2012 Nov, 56(11): 5794-803 Activation of the unfolded protein response by 2-deoxy-D-glucose Inhibits Kaposi’s Sarcoma-associated herpesvirus replication and gene expression. Antimicrobial Agents and Chemotherapeutics. PMID: 22926574.

Ma Q, Cavallin LE, Leung HJ, Chiozzini C, Goldschmidt-Clermont PJ, Mesri EA. 2013. A role for virally induced reactive oxygen species in Kaposi’s Sarcoma herpesvirus tumorigenesis. Antioxidants and Redox Signaling. PMID: 22746102

Croci DO, Salatino M, Rubinstein N, Cerliani JP, Cavallin LE, Leung HJ, Ouyang J, Ilarregui JM, Toscano MA, Domaica CI, Croci MC, Shipp MA, Mesri EA, Albini A, Rabinovich GA. 2012. Disrupting galectin-1 interactions with N-glycans suppresses hypoxia-driven angiogenesis and tumorigenesis in Kaposi’s sarcoma. Journal of Experimental Medicine. PMID: 23027923

NAME: Matthew Tsai- PROGRAM: Microbiology & Immunology – YEAR OF STUDY: MS4 – MENTOR: Eckhard R. Podack, MD.,PhD

Schreiber TH, Wolf D, Tsai MS, Chirinos J, Deyev VV, Gonzalez L, Levy RB, Podack ER. TNFRSF25 Mediated in vivo Expansion of Regulatory T Cells to Control Autoaggressive Disease. Accepted with Revisions at the Journal of Clinical Investigation.

Tsai MS, Schreiber TH, McCormack R, Podack ER. “Reversal of airway remodeling in chronic allergic lung inflammation by agonist of TNF-receptor super family member 25.” Currently Under Review

Schreiber TH, Wolf D, Tsai MS, Chirinos J, Deyev VV, Gonzalez L, Malek TR, Levy, RB, Podack ER. “Therapeutic Treg expansion in mice by TNFRSF25 prevents allergic lung inflammation.” Journal of Clinical Investigation 120.10 (2010): 3629-3640 PMID: 20890040

NAME: Ansel Amaral- PROGRAM: Molecular & Cellular Pharmacology- YEAR OF STUDY MS4 – MENTOR: Christian Faul, PhD

Mangos, S, Amaral, AP, Faul, C, Juppner H, Reiser, J, Wolf, M., 2012, Expression of fgf23 and αklotho in developing embroyonic tissues and adult kidney of the zebrafish, Danio rerio, Nephrology Dial Transplant, Dec, 27(12): 4314-22, PMID 22885518

Scialla JJ, Lau WL, Reilly, MP, Isakova, T, Yang HY, Crouthamel, MH, Chavkin NW, Rahman, M, Wahl, P, Amaral, AP, Hamano T, Master SR, Nessel L, Chai B, Xie, D, Kallem RR, Chen J, Lash JP, Jusek et al, 2013, Fibroblast growth factor 23 is not associated with and does not induce arterial calcification, Kidney Int. June; 83(6): 1159-68, PMID: 23389416

Faul, C, Amaral AP, Oskouei B, Hu, Mc et al, 2011, FGF23 Induces left ventricular hypertrophy, J. Clin. Invest, Nov, 121(11): 4393-408 PMID: 21985788

Wolf, M, Molnar MZ, Amaral, AP et al, 2011, Elevated fibroblast growth factor 23 is a risk factor for kidney transplant loss and mortality, J. Am. Soc. Nephrology, May; 22(5): 956-66, PMID: 21436289

NAME Stephanie Adamczak- PROGRAM Neuroscience – YEAR OF STUDY MS4 – MENTOR: Stephan Züchner, MD

Adamczak S, Dale G, de Rivero Vaccari JP, Bullock, MR, Dietrich WD, Keane RW (2012) Inflammasome proteins in cerebrospinal fluid of brain injured patients are potential biomarkers of functional outcome, J. Neurosurgery 117:1119-25. PMCID: PMC3576729

Adamczak S, de Rivero Vaccari JP, Dale G, Nonner D, Dahl G, Bullock MR, Dietrich WD, Keane RW (2012). Pyroptotic neuronal cell death mediated by the AIM2 inflammasome. In Review.

NAME: David Landy- DEPT: Epidemiology & Public Health – YEAR OF STUDY MS4 – MENTOR: Steven Lipshultz, MD & Jay Wilkinson, MD., PhD

Landy, DC, Lipsitz, SR, Kurtz, JM, Hinkle, AS, Constine, LS, Adams, MJ, Lipshultz, SE, Miller, TL, 2013, Dietary quality, caloric intake, and adiposity of childhood cancer survirors and their siblings: an analysis from the cardiac risk factors in childhood cancer survivors study, Nutr. Cancer. 65(4):547-55 PMID:23659446

Landy, DC, Miller, TL, Lipsitz, SR, Lopez-Mitnik, G, Hinkle AS, Constine LS, Adams, MJ, Lipshultz, SE, 2013, Cranial irradiation as an additional risk factor for anthracycline cardiotoxity in childhood cancer survivors: an analysis from the cardiac risk factors in childhood cancer survivors study, Pediatric Cardiology, Apr, 34(4):826-34 PMID:23080542

Quintero RA, Kontopoulos, EV, Quintero, LF, Landy DC, Gonzalez, R, Chmait RH, 2013, The observed vs. expected lung-to-head ratio does not correct for the effect of gestational age on the lung –to-head ratio, J. Maternal Fetal Neonatal Med. Apr, 26(6):552-7 PMID: 23046345

Landy, DC, Gorin, MA, Egusquiza JD, Weiss, J, O’Connell MT, 2012, Medical Student attitudes before and after participation in rural health fairs, J. Res. Med. Sci, Mar, 17(3): 298-303, PMID: 23267384

Landy DC, Mintzer MJ, Dearwater SR, Graygo JA, Schulman CI, 2012, Fatal Falls in an ethnically diverse urban community: the link between demographic factors and the circumstances surrounding fatal falls, South Med. J. Aug; 105(8):405-10, PMID:22864096

NAME Michael Kritzer-Cheren- PROGRAM: Molecular & Cellular Pharmacology- YEAR OF STUDY: MS3 – MENTOR: Michael Kapiloff, MD., PhD

Kritzer, M.D., Li, J., Dodge-Kafka, K.L., and Kapiloff, M.S. AKAPs: 2012, The Architectura Underpinnings of Local cAMP signaling, Journal of Molecular and Cellular Cardiology, 52 (2): 351-358,. PMC3168680

Li, J., Kritzer, M.D., Carlisle Michel, J.J., Le, A., Thakur, H., Gayanilo, M., Passariello, C., Negro, A., Danial, J.B., Oskouei, B., Sanders, M., Hare, J.M., Hanauer, A., Dodge Kafka, K.L., and Kapiloff, M.S. 2013, Anchored p90 Ribosomal S6 Kinase 3 is Required for Concentric Cardiac Myocyte Hypertrophy. Circulation Research, 112: 128-139, PMC3537852

Passariello, C, Gayanilo, M, Kritzer MD, Thakur, H, Cozacov, Z, Rusconi, F, Wieczorek, DF, Sanders, M, Li, J. Kapiloff, MS, 2013, P90 ribosomal S6 Kinase 3 Contributes to Cardiac Insufficiency in a-tropomyosin Glu180Gly Transgenic Mic, Am J Physiolog Heart Circ. Physiology Aug, PMID 23913705

NAME: Akintomide Apara- DEPT: Neuroscience – YEAR OF STUDY MS3 – MENTOR: Jeffrey Goldberg, MD., PhD

Moore D, Apara A, Goldberg JL. 2011 Kruppel-Like Transcription Factors in the Nervous System: Novel players in neurite growth and axon regeneration. Mol Cell Neurosci. Aug;47(4):233-43. PMID: 21635952

Tang X, Narayanan S, Peruzzi G, Apara A, Natarajan K, Margulies DH, Coligan JE, Borrego F. 2009, A single residue, arginine 65, is critical for the functional interaction of leukocyte-associated inhibitory receptor-1 with collagens. J Immunol. May 1;182(9):5446-52. PMID: 19380792

NAME Gustavo Munguba- PROGRAM: Neuroscience- YEAR OF STUDY: MS3 – MENTOR: Richard Lee, MD., PhD

Munguba GC, Geisert EE, Williams RW, Tapia ML, Lam DK, Bhattacharya SK, Lee RK. Effects of Glaucoma on Chrna6 Expression in the Retina. Curr Eye Res. 2012 Sep 24 Epub ahead of print. PMID: 23002780

Camp AS, Ruggeri M, Munguba GC, Tapia ML, John SW, Bhattacharya SK, Lee RK. Structural correlation between the nerve fiber layer and retinal ganglion cell loss in mice with targeted disruption of the Brn3b gene. Invest Ophthalmol Vis Sci. 2011 Jul 13;52(8):5226-32. PMID: 21622702

Munguba GC, Camp AS, Risco M, Tapia ML, Bhattacharya SK, Lee RK. Vesicular glutamate transporter 3 in age-dependent optic neuropathy. Mol Vis. 2011 Feb 5;17:413-9. PMID: 21311743

NAME: Stephanie Peacock- PROGRAM: Cancer Biology- YEAR OF STUDY: MS3 – MENTOR: Kerry Burnstein, PhD

Peacock S, Fahrenholtz C, Burnstein K. Vav3 Enhances Androgen Receptor Splice Variant Activity and Is Critical for Castration-Resistant Prostate Cancer Growth and Survival. Mol Endo. 2012 Dec;26(12):1967-79. Epub 2012 Sep 28. PMCID: PMC3517715

Wu F, Peacock S, Rao S, Lemmon S, Burnstein K. Novel Interaction Between the Co-chaperone Cdc37 and Rho GTPase Exchange Factor Vav3 Promotes Androgen Receptor Activity and Prostate Cancer Growth. J Biol Chem. Epub 2012 Dec 31. PMC3581368.

NAME: Diana Kachan – PROGRAM: Epidemiology & Public Health- YEAR OF STUDY: – MENTOR: David Lee, PhD

Kachan D, Fleming LE, LeBlanc WG, Goodman E, Arheart KL, Caban Martinez AJ, Clarke T, Ocasio MA, Christ S, Lee DJ. Worker populations at risk for work-related injuries across the life course. American Journal of Industrial Medicine. 2012. 55(4): 361-366. PMID: 22170632

Tannenbaum SL, Kachan D, Fernandez CA, McClure LA, LeBlanc WG, Arheart KL, Lee DJ. State Variations of Chronic Disease Risk Factors in Older Americans. Preventing Chronic Disease. 2012. 9. PMID: 23256910

Kachan D, Davila E, Lewis JE, Fleming LE, Lee DJ, Arheart K, LeBlanc WG, Caban Martinez A. Nutrient Intake and Dietary Recommendation Adherence among US Workers. Journal of Occupational and Environmental Medicine. 2012. 54(1): 101-105. PMID: 22193114

Lee DJ, Fleming LE, LeBlanc WG, Arheart KL, Ferraro KF, Pitt-Catsouphes M, Muntaner C, Fernandez CA, Caban-Martinez AJ, Davila EP, Bandiera FC, Lewis JE, Kachan D. Health Status and Risk Indicator Trends of the Aging U.S. Healthcare Workforce. Journal of Occupational and Environmental Medicine. 2012. 54(4): 497-503PMID: 22446575

NAME: Mary McKuen- PROGRAM: Microbiology & Immunology- YEAR OF STUDY GS4 – MENTOR: Kenneth Fields, PhD

McKuen, M., Dahl, G., and Fields, K.A. 2013. Assessing a potential role of host Pannexin 1 during Chlamydia trachomatis infection. PloS ONE. 8:e63732 2013 May 20;8(5):e63732. doi: 10.1371/journal.pone.0063732. PMID: 23700432

NAME: Samuel Beckerman – PROGRAM: Neuroscience. YEAR OF STUDY: GS3 – MENTORV: Vance Lemmon, PhD

Luo X, Salgueiro Y, Beckerman SR, Lemmon VP, Tsoulfas P, Park KK., 2013, “Three dimensional evaluation of retinal ganglion cell axon regeneration and pathfinding in whole mouse tissue after injury” Experimental Neurology, doi:pii: S0014-4886(13)00084-8.10.1016/j.expneurol.2013.03.001. PMID: 23510761

Kitagawa R, Van Haren R, Yokobori S, Cohen D. Beckerman SR, Ahmad F, Bullock MR., 2013, “Management of Simultaneous Traumatic Brain and Aortic Injury” Journal of Neurosurgery, PMID: 23767893

Rosenbaum J, Basu S, Beckerman S, Werner T, Torigian DA, Alavi A., 2011, “Evaluation of diagnostic performance of 18F-FDG-PET compared to CT in detecting potential causes of fever of unknown origin in an academic centre” Hell J Nucl Med. 2011 Sep-Dec;14(3):255-9. PMID: 22087445

NAME Alexandra Besser – PROGRAM: Neuroscience – YEAR OF STUDY GS3 – MENTOR Joyce Slingerland MD.,PhD

Wander, SA, Zhao, D, Besser AH, Hong, F, Wei, J, Ince, TA, Milikowski, C, Bishopric NH, Minn, AJ, Creighton, CJ, Slingerland, JM, 2013, P13K/mTOR inhibition can impair tumor invasion and metastasis in vivo despite a lack of antiproliferative action in vitro: implications for targeted therapy, Breast Cancer Res. Treat. 2013 April, 138(2): 369-81, PMC:3608882

NAME: Ryan McCormack- PROGRAM: Microbiology & Immunology – YEAR OF STUDY GS3 -MENTOR: Eckhard Podack, MD., PhD

Ali, Y.O., McCormack, R., Darr, A., and Zhai, R.G. (2011). Nicotinamide mononucleotide adenylyltransferase is a stress response protein regulated by the heat shock factor/hypoxia-inducible factor 1alpha pathway. The Journal of biological chemistry 286, 19089-19099. PMID: 21478149

Kitay, B.M., McCormack, R., Wang, Y., Tsoulfas, P., and Zhai, R.G. (2013). Mislocalization of neuronal mitochondria reveals regulation of Wallerian degeneration and NMNAT/WLD-mediated axon protection independent of axonal mitochondria. Human molecular genetics 22, 1601-1614. PMID: 23314018

McCormack, R., de Armas, L.R., Shiratsuchi, M., Ramos, J.E., and Podack, E.R. (2013). Inhibition of intracellular bacterial replication in fibroblasts is dependent on the perforin-like protein (perforin-2) encoded by macrophage-expressed gene 1. Journal of innate immunity 5, 185-194. PMID: 23257510

Fields, K.A., McCormack, R., de Armas, L.R., and Podack, E.R. (2013). Perforin-2 restricts growth of Chlamydia trachomatis in macrophages. Infection and immunity. PMID:23753625

NAME: Srinivasan Narayanan- PROGRAM: Neuroscience – YEAR OF STUDY: GR3 – MENTOR Miguel Perez-Pinzon, PhD

Narayanan, SV, Dave, KD, Perez-Pinzon, MA. Ischemic Preconditioning and Clinical Scenarios. Current Opinion in Neurology. 26(1): 1-7. 2013. PMID: 23197083

Thompson, JW*, Narayanan, SV*, Perez-Pinzon, MA. Redox Pathways involved in Ischemic Preconditioning. Current Neuropharmacology.10(4): 354-369. 2012. *co-first authors

Book Chapter: Narayanan SV*, Neumann J*, Morris KC, Perez-Pinzon MA. Ischemic preconditioning – mediated signaling pathways leading to tolerance against cerebral ischemia. Innate Neuroprotection for Stroke. Springer Publishing, 1st edition, March 2012. *co-first authors

NAME Veronica Peaschansky- PROGRAM Neuroscience – YEAR OF STUDY GS3 – MENTORClaes Wahlestedt, MD., PhD

VJ Peschansky, Z Liang, C Wahlestedt. RNAi Joins the “Singles Club”. Molecular Therapy. 2012 Nov; 20(11):2010-1. PMCID: 23131851

NAME: Eric Bray- PROGRAM: Neuroscience – YEAR OF STUDY GS1 – MENTOR: Kevin Park, PhD

Justin Sick, Eric Bray, Amade Bregy, Dalton Dietrich, Helen M Bramlett and Thomas J Sick, 2012: EEGgui: A Program Used to Detect Electroencephalogram Anomalies After Traumatic Brain Injury; Source Code for Biology and Medicine (awaiting review)

NAME: Matthew Phillips- PROGRAM: Microbiology & Immunology – YEAR OF STUDY GS1- MENTOR: Maria Abreu, MD

Hower, S., Phillips, M. C., Brodsky, M., Dameron, A., Tamargo, M., Salazar, N. C., Jackson, C. R., Barrett, J. B., Davidson, M., Davis, J., Mukherjee, S., Ewing, R. Y., Gidley, M. L., Sinigalliano, C. D., Johns, L., Johnson III, F. E., Adebanjo, O., Plano, L. R. W.; 2013, Clonally related methicillin-resistant Staphylococcus aureus isolated from short-finned pilot whales (Globicephala macrorhynchus), human volunteers, and a bayfront cetacean rehabilitation facility. Microbial Ecology, 65 4: pp 1024-1038. PMID: 23508733

Abdelzaher, AM, Solo-Gabriele HM, Phillips, MC, Elmir SM, Fleming LE, 2013, An alternative approach to water regulations for public health protection at bathing beaches, J. Environ. Public Health 2013: , Jan.13852, PMID: 23431320

Piggot, AM, Klaus JS, Johnson S, Phillips MC, Solo-Gabriele HM, 2012, Relationship between enterococcal levels and sediment biofilms at recreational beaches in South Florida, Appl. Environ. Microbiology, Sep; 78(17):5973-82, PMID: 22706061.

Enns AA, Vogel LJ, Abdelzaher AM, Solo-Gabriele HM, Plano LR, Gidley ML, Phillips MC, Klaus JS, Piggot AM, Feng Z, Reniers AJ, Haus BK, Elmir SM, Zhang Y, Jimenez NH, Abdel-Mottaleb N, Schoor ME, Brown A, Khan SQ, Dameron AS, Salazar NC, Fleming LE, 2012, Spatial and temporal variation in indicator microbe sampling is influential in beach management decisions, May 1; 46(7): 2237-46, PMCID: 3304019

NAME: Ezra Blumenthal- PROGRAM: Undecided – YEAR OF STUDY MS2- MENTOR: Undecided

Soderblom, C., Luo, X., Blumenthal, E., Bray, E., Lyapichev, K., Ramos, J., Krishnan, V., Lai-Hsu, C., Park, K.K., Tsoulfas, P., Lee, J.K 2013, Perivascular Fibroblasts form the fibrotic scar after contusive spinal cord injury, submitted to Journal of Neuroscience. In press